Table 1.
Patients characteristics and endoscopic and histologic findings.
| Variable | Overall (N = 16) 1995–2005 | Overall (N = 73) 2005–2015 | P-value |
|---|---|---|---|
| Mean age at diagnosis (SD) | 10 (6) | 7.5 (5.2) | 0.64 |
| Male, No. (%) | 10 (62.5%) | 49 (67.1%) | 0.87 |
| Presenting symptom | |||
| Vomiting | 6 (43.5%) | 30 (41.1%) | 0.84 |
| Dysphagia | 10 (60.9%) | 26 (35.6%) | 0.032 |
| Abdominal pain | 5 (30.4%) | 19 (26.0%) | 0.68 |
| Food impaction | 3 (21.7%) | 7 (9.6%) | 0.12 |
| Failure to thrive | Unavailable data | 6 (8.2%) | |
| Duration of symptoms Mean (month) | Unavailable data | 13 | |
| History of asthma | 7/11 (63.6%) | 29 (39.7%) | 0.14 |
| Data available on 11 children | |||
| History of eczema | Unavailable data | 18 (24.7%) | |
| History of allergic rhinitis | 7/13 (53.8%) | 45 (61.6%) | 0.60 |
| Data available on 13 children | |||
| History of food allergy | 8/14 (57.1%) | 35 (47.9%) | 0.53 |
| Data available on 14 children | |||
| Family history of EoE | 6 (37.5%) | 2 (2.7%) | <0.001 |
| Esophageal endoscopic findings | |||
| Normal | 10 (65.2%) | 16 (21.9%) | <0.001 |
| Linear furrows | 5 (30.4%) | 58 (79.5%) | <0.001 |
| White plaques | 0 (0%) | 31 (42.5%) | <0.001 |
| Trachealization | 1 (<1%) | 5 (6.8%) | 0.67 |
| Stricture | 0 (0%) | 0 (0%) | – |
| Mean eosinophil count/HPF on esophageal biopsies | 0.20 | ||
| 15–30 | 7 (39.2%) | 33 (45.2%) | |
| 31–45 | 4 (26%) | 8 (11.0%) | |
| >45 | 5 (34.8%) | 32 (43.8%) |