Fig. 1.

Hierarchical clustering of genes whose expression was different in non-diabetic and T1D mice. The list of genes was identified with a T test unpaired unequal variance (p < 0.005, no multiple test correction) of mRNA expression data. The color of the rectangles representing averaged expression values for each gene in each set of samples (n = 3 for B6 and n = 3 for Akita) indicates the degree of increase (red) or decrease (blue) of each gene expression signal relative to the mean signal intensity (yellow).