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. 2018 Nov 27;8:1–9. doi: 10.1016/j.ijppaw.2018.11.005

Table 1.

Inoculation of γ-interferon knockout mice with Besnoitia tarandi bradyzoites obtained from the skin of a Canadian caribou.

Mouse Caribou Treatment of tissue Inoculation dose Route of inoculation End of experiment (dpi) PCRd result
K280-1 H-1145 Mechanical 1.2 E+06a ipb 9c Positive
K280-2 H-1145 Mechanical 1.2 E+06 ip 8c Positive
K281-1 H-1146 Mechanical 1.5 E+06 ip 18c Positive
K281-2 H-1146 Mechanical 1.5 E+06 ip 42 NDe
K282-1 H-1145 Mechanical + Pepsin 1.5 E+06 ip 42 ND
K282-2 H-1145 Mechanical + Pepsin 1.5 E+06 ip 42 ND
K283-1 H-1145 Peritoneal parasites of K280-2 3.0 E+04 ip 5c Positive
K283-2 H-1145 Peritoneal parasites of K280-2 3.0 E+04 ip 5c Positive
a

1 × 104 bradyzoites of this preparation were also inoculated on MARC145 cell culture.

b

Intraperitoneal.

c

Experiment was terminated due to signs of disease (ruffled coat, lethargy).

d

For details see Table 2.

e

ND = Not determined.