Table 3.
Differentially expressed proteins in the retina as identified by 2D DIGE. Table shows the identification of protein spots highlighted in Fig. 2 following mass spectral analysis. Fold differences in expression between normal retina (N), and gliotic retina (G) are shown.
| Spot | Uniprot ID | Accession | Peptide count | Protein name | Fold difference |
|---|---|---|---|---|---|
| G/N | |||||
| Spot 788 | AMPL_HUMAN | P28838 | 5 | Cytosol aminopeptidase | 2.06 |
| Spot 1567 | GFAP_HUMAN | P14136 | 38 | Glial fibrillary acidic protein | 2.05 |
| Spot 1568 | ENOA_HUMAN | P06733 | 29 | Alpha-enolase | 0.45 |
| Spot 891 | ENOA_HUMAN | P06733 | 25 | Alpha-enolase | 0.43 |
| Spot 1561 | DDAH1_HUMAN | O94760 | 16 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | 0.45 |
| Spot 1603 | CAH2_HUMAN | P00918 | 15 | Carbonic anhydrase 2 | 0.43 |
| Spot 820 | ARRS_HUMAN | P10523 | 11 | S-arrestin | 0.27 |
| Spot 1553 | ARRS_HUMAN | P10523 | 3 | S-arrestin | 0.26 |
| Spot 1080 | DDAH1_HUMAN | O94760 | 4 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | 0.49 |
| Spot 831 | ARRS_HUMAN | P10523 | 3 | S-arrestin | 0.38 |
| Spot 1125 | G3P_HUMAN | P04406 | 28 | GAPDH | 0.32 |
| Spot 1005 | VIME_HUMAN | P08670 | 44 | Vimentin | 2.67 |
| Spot 759 | PDIA1_HUMAN | P07237 | 17 | Protein disulphide-isomerase | 1.30 |
| Spot 943 | VIME_HUMAN | P08670 | 66 | Vimentin | 2.13 |