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Histomolecular characteristics of anaplastic meningiomas
| De Novo Anaplastic Meningiomas n = 28 | Progressing Anaplastic Meningiomas n = 29 | |
|---|---|---|
| Number of relapses before switch to grade III | ||
| 1 | — | 12 |
| 2 | — | 5 |
| 3 | — | 7 |
| 4 | — | 2 |
| 5 | — | 5 |
| Number of mitoses at diagnosis of grade III histology | ||
| >20 | 21 | 29 |
| 15–20 | 1 | 0 |
| 5–10 | 2 | 0 |
| <5 | 4 | 0 |
| Histological anaplasia | ||
| with elevated number of mitoses | 11 | 20 |
| without elevated number of mitoses | 7 | 0 |
| TERT promoter mutation | 5/28 | 3/29 |
| TERT promoter methylation | 11/14 | 19/19 |
