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Phase II primary endpoints
| RCT | Non-RCT | Total | |
|---|---|---|---|
| Progression-free survival | 13 (8%) | 85 (51%) | 98 (59%) |
| Overall survival | 11 (7%) | 34 (20%) | 45 (27%) |
| Safety/toxicity/MTD | 7 (4%) | 19 (11%) | 26 (16%) |
| Imaging/response | 3 (2%) | 28 (17%) | 31 (19%) |
| PK/PD | 2 (1%) | 5 (3%) | 7 (4%) |
| Other | 4 (2%) | 4 (2%) | |
| Total | 25 (15%) | 141 (85%) | 166 (100%) |
