Table 5.
Noncompartmental pharmacokinetic parameters of pinosylvin in rats after oral administration (n=6, means ± SD).
| Pharmacokinetic parameters | Unit | Value |
|---|---|---|
| t1/2 | h | 1.347±0.01 |
| Tmax | h | 0.137±0.016 |
| Vd | L/kg | 434.716±25.508 |
| CL | L/h/kg | 223.635±11.866 |
| Cmax | ng/ml | 164.231±64.264 |
| MRT0-t | h | 3.209±0.129 |
| MRT0-∞ | h | 3.210±0.129 |
| AUC0-24h | ng/ml h | 711.142±46.885 |
| AUC0-∞ | ng/ml h | 711.195±46.885 |
T1/2: elimination half-life; Tmax: time to peak concentration; Vd: volume of distribution; CL: clearance; Cmax: peak plasma concentration; MRT: mean retention time; AUC: area under the curve.