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. 2018 Oct 29;5(4):R115–R125. doi: 10.1530/ERP-18-0056

Table 2.

Basic finding and validation of machine learning applications in the field of echocardiography.

Study Year Application Machine learning model used Training/validation set Test set Limit of agreements and bias Sensitivity/Specificity/Accuracy AUC Time required for measurement
(7) 2018 Recognise 15 echocardiography views Convolutional neural network 200,000 images 20,000 images –/–/91.7% 0.996 21 ms/image
(54) 2018 Quantification of wall motion abnormalities Double density-dual tree discrete wavelet transform 279 images 96.12%/96%/96.05%
(55) 2018 Quantification of wall motion abnormalities Convolutional neural network 4392 maps 61 subjects 81.1%/65.4%/75%
(36) 2017 Recognition/classification of apical views Supervised dictionary learning 210 clips 99 clips –/–/95% 0.05 ± 0.003 s per clip
(57) 2017 Assessment of myocardial velocity Unsupervised multiple kernel learning 55 subjects Avg 51.7% Avg 73.25%/78.4%/– <30 s
(5) 2016 Classification/discrimination of pathological patterns (HCM vs ATH) Support vector machine, random forest, artificial neural network 96%/77%/– 0.795 8 s
(27) 2016 Classification/discrimination of pathological patterns (RCM vs CP) Associative memory-based machine-learning algorithm –/–/93.7% 0.962
(47) 2016 Quantification of MR Support vector machine 5004 frames 99.38%/99.63%/99.45%
(24) 2015 Calculation of EF and LS AutoEF Software 255 patients 0.83 (0.78 to 0.86) and −0.3 (1.5 to 0.9) 8 ± 1 s/patient
(37) 2013 Automated detection of LV border Random forest classifier with an active shape model 50 images 35 images –/–/90.09%
(53) 2011 Quantification of wall motion abnormalities Relevance Vector Machine classifier 173 patients –/–/93.02%
(56) 2008 Quantification of wall motion abnormalities Hidden Markov model 24 studies (720 frames) 20 studies (600 frames) –/–/84.17%
(39) 2008 Calculation of EF AutoEF Software 10,000 images 92 patients 1% (−19% to 33%)
(38) 2007 Calculation of EF AutoEF Software >10,000 images 200 patients 6% (−2.87 to 2.91) <15 s per view

ATH, athletes’ heart; Avg, average; CP, constrictive pericarditis; EF, ejection fraction; HCM, hypertrophic cardiomyopathy; LS, longitudinal strain; LV, left ventricle; MR, mitral regurgitation; ms, milliseconds; RCA, restrictive cardiomyopathy; s, seconds.