Table 3.
Effects of catalpol on left ventricular function in ISO-induced myocardial infarction in rats
| Groups | Number | +LVdp/dtmax (mm Hg) | –LVdp/dtmax (mm Hg) | LVEDP (mm Hg) | LVSP (mm Hg) |
|---|---|---|---|---|---|
| Control | 8 | 3733.01±273.04 | 3367.01±240.02 | 4.85±0.86 | 151.63±12.72 |
| ISO | 7 | 2730.14±278.57## | 2524.14±295.76## | 17.34±1.09## | 122.71±11.43## |
| Catalpol (L) | 8 | 3160.37±282.43* | 2674.50±213.73 | 13.58±0.70** | 126.63±9.47 |
| Catalpol (H) | 8 | 3346.38±306.01** | 3120.13±174.08** | 11.34±1.15** | 143.38±10.39** |
Catalpol (L) - low-dose catalpol; Catalpol (H) - high-dose catalpol; +LVdp/dtmax - left ventricular maximum rate of positive pressure development; −LVdp/dtmax - left ventricular maximum rate of negative pressure development; LVEDP - left ventricular end-diastolic pressure; LVSP - left ventricular systolic pressure.
#P<0.05,
##
P<0.01 versus control group;
*
P<0.05,
**
P<0.01 versus ISO group