Table 3.

Histology and quantitative immunohistochemistry

Mean grade of staining
mm mm	All Patients	AD+	AD–	P-value
Adventitia
T-cells	1.4±0.2	1.8±0.3	1.1±0.2	0.077
B-cells	1.0±0.2	1.2±0.4	1.0±0.2	0.791
Macrophages	1.8±0.2	2.2±0.2	1.5±0.2	0.068
Plasma cells	0.6±0.2	0.9±0.3	0.6±0.2	0.201
Inflammation	1.6±0.2	2.2±0.3	1.3±0.2	0.003
Proliferation	1.5±0.2	1.6±0.2	1.3±0.4	0.561
Media
T-cells	0.6±0.2	0.8±0.3	0.5±0.2	0.476
B-cells	0.2±0.1	0.3±0.2	0.1±0.6	0.175
Macrophages	1.2±0.2	1.5±0.3	1.0±0.3	0.207
Plasma cells	0.4±0.2	0.3±0.2	0.5±0.4	0.424
Inflammation	0.8 ± 0.2	1.4±0.3	0.3±0.1	0.001
Proliferation	0.9±0.2	1.5±0.3	0.4±0.2	0.002
Degeneration	1.5±0.2	1.7±0.3	1.4±0.3	0.466
Elastase	1.6±0.2	1.6±0.2	1.6±0.3	0.968
Intima
T-cells	1.0±0.2	1.4±0.2	0.6±0.2	0.006
B-cells	0.1±0.1	0.3±0.2	0	0.072
Macrophages	1.5±0.2	1.9±0.2	1.2±0.2	0.032
Plasma cells	0.7±0.2	0.7±0.2	0.5±0.4	0.622
Inflammation	1.1±0.2	1.6±0.3	0.7±0.2	0.005
Proliferation	0.9±0.2	1.0±0.2	0.5±0.4	0.206
Thickness	2.0±0.3	1.9±0.3	2.1±0.4	0.706
Cellularity	1.6±0.2	1.7±0.2	1.3±0.2	0.328

Mean grade of staining expressed as point score units/mm²

AD - aortic dissection