Table 3.

Different metabolites between LP and HG.

No.	Differential metabolites	VIP	P	FC	Tendency	Class
1	Beta-alanine	2.6	≤0.001	0.32	↓	Amino acid
2	Creatinine	1.8	≤0.001	0.68	↓	Amino acid
3	L-Asparagine	1.6	≤0.001	1.33	↑	Amino acid
4	L-Tyrosine	1.7	0.001	1.44	↑	Amino acid
5	D-Threitol	1.8	≤0.001	1.70	↑	Carbohydrate
6	Rhamnose	2.0	≤0.001	1.72	↑	Carbohydrate
7	L-Sorbose	1.7	≤0.001	0.53	↓	Carbohydrate
8	D-Fructose	1.7	≤0.001	0.53	↓	Carbohydrate
9	Gluconolactone	1.8	≤0.001	1.86	↑	Carbohydrate
10	Sucrose	1.6	≤0.001	2.01	↑	Carbohydrate
11	D-Maltose	1.7	≤0.001	79.59	↑	Carbohydrate
12	Pelargonic acid	2.0	≤0.001	1.90	↑	Fatty acid
13	Tetracosanoic acid	1.8	≤0.001	1.32	↑	Fatty acid
14	Normetanephrine	1.7	≤0.001	0.72	↓	Hormone
15	Tryptamine	1.6	≤0.001	0.62	↓	Indoles
16	Uracil	1.6	0.001	1.97	↑	Nucleotide
17	Inosine	2.0	≤0.001	5.15	↑	Nucleotide
18	Malic acid	1.6	0.002	1.78	↑	Organic acids
19	Oxoglutaric acid	1.8	≤0.001	3.22	↑	Organic acids
20	Taurine	1.8	≤0.001	0.45	↓	Organic acids
21	Citric acid	1.8	≤0.001	2.51	↑	Organic acids
22	Isocitric acid	2.1	≤0.001	2.76	↑	Organic acids

FC, fold change; VIP, variable importance in projection. ↑, the content of this metabolite was higher in the group of latent pattern (LP) than in the healthy group; ↓, the content of this metabolite was lower.