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. 2018 Dec 4;6:141. doi: 10.1186/s40425-018-0463-2

Fig. 3.

Fig. 3

Early Markers of Response Are Associated with Progression-Free Survival. a Kaplan-Meier curve showing that patients with <= median percentage of MDSCs at baseline had prolonged PFS. b Change in CTC numeration from C1D1 to C3D1. c Decrease or no change in in CTC count from C1D1 to C1D15 correlated with increased PFS. d Kaplan-Meier curve demonstrating that increased DC maturity (as demonstrated by CD83 expression on CD141+ mDCs from baseline to C1D15) was associated with prolonged PFS. e Kaplan-Meier curve demonstrating that patients with > median percentage of K67+PD1+CD8+ T cells among total CD8+ T cells at C1D15 had prolonged PFS. f Kaplan-Meier curve demonstrating that patients with > median percentage of K67+PD 1+CD4+ T cells among total CD4+ T cells at C3D1 had prolonged PFS