Table 4.
Hazard ratios (95% CI) of colon, rectal and colorectal cancers by changes in physical activity level between enrollment and follow-up (n = 44,498) in the NOWAC Study
| Changes in physical activity level | ||||||
|---|---|---|---|---|---|---|
| Cancer | Models | Consistently active (PA 7–10) [n = 9417] |
Consistently moderately active (PA 5–6) [n = 13,189] |
Increased PA [n = 7869] |
Decreased PA [n = 6317] |
Consistently inactive (PA 1–4) [n = 7706] |
| Colon | Age-adjusted N of cases: 393 |
0.83 (0.62–1.11) 69 |
1.00 134 |
0.70 (0.51–0.97)
51 |
0.85 (0.62–1.16) 58 |
0.91 (0.69–1.20) 81 |
| Multivariable 1 N of cases: 393 |
0.86 (0.64–1.15) 69 |
1.00 134 |
0.69 (0.50–0.96)
51 |
0.82 (0.60–1.11) 58 |
0.86 (0.65–1.14) 81 |
|
| Multivariable 2 N of cases: 393 |
0.87 (0.65–1.16) 69 |
1.00 134 |
0.69 (0.50–0.95)
51 |
0.81 (0.60–1.11) 58 |
0.86 (0.65–1.14) 81 |
|
| Rectal | Age-adjusted N of cases: 168 |
1.57 (1.03–2.41)
43 |
1.00 42 |
1.36 (0.86–2.16) 32 |
1.16 (0.70–1.91) 24 |
1.02 (0.63–1.66) 27 |
| Multivariable 1 N of cases: 168 |
1.54 (1.01–2.37)
43 |
1.00 42 |
1.34 (0.84–2.12) 32 |
1.11 (0.67–1.84) 24 |
1.02 (0.62–1.66) 27 |
|
| Multivariable 2 N of cases: 168 |
1.57 (1.02–2.42)
43 |
1.00 42 |
1.32 (0.83–2.10) 32 |
1.11 (0.67–2.84) 24 |
1.00 (0.61–1.63) 27 |
|
| Colorectal | Age-adjusted N of cases: 561 |
1.01 (0.80–1.28) 112 |
1.00 176 |
0.86 (0.67–1.12) 83 |
0.92 (0.71–1.20) 82 |
0.94 (0.74–1.20) 108 |
| Multivariable 1 N of cases: 561 |
1.03 (0.81–1.31) 112 |
1.00 176 |
0.85 (0.65–1.10) 83 |
0.89 (0.68–1.15) 82 |
0.90 (0.71–1.15) 108 |
|
| Multivariable 2 N of cases: 561 |
1.04 (0.82–1.32) 112 |
1.00 176 |
0.84 (0.65–1.10) 83 |
0.88 (0.68–1.15) 82 |
0.90 (0.70–1.15) 108 |
|
Multivariable 1 = adjusted for age, height, body mass index, duration of education, alcohol consumption, and smoking status
Multivariable 2 = additionally adjusted for intake of red meat, processed meat, dietary calcium, and dietary fibre
Confidence intervals in bold have p-values less than 0.05