Table 6.
Clinical sign, lesions and laboratory abnormalities reported in association with Bartonella infections in cats, dogs and humans
| Bartonella spp. | Hostsa | ||
|---|---|---|---|
| Cats | Dogsb | Humans | |
| B. henselae | Anemia (EI); diaphragmatic myositis (NI); endocarditis (NI); endomyocarditis - left ventricular; endocardial fibrosis complex (NI); eosinophilia (NI); fever (EI, NI); hyperglobulinemia (EI, NI); lethargy (EI, NI); lymphadenomegaly (EI); mild neurological signs (EI); pyogranulomatous myocarditis and uveitis, conjunctivitis, keratitis and corneal ulcers (NI); subclinical (EI, NI); thrombocytopenia (NI) | Endocarditis (NI); eosinophilia (NI); epistaxis(NI); fever (NI); granulomatous hepatitis (NI); granulomatous inflammation (NI); hyperglobulinemia (NI); hyperinsulinemic hypoglycemia syndrome (NI); ineffective erythropoiesis (NI); lymphadenomegaly (NI); monoclonal gammopathy (NI); peliosis hepatis (NI); subclinical (EI, NI); thrombocytopenia (NI); vasoproliferative lesions (NI) | Arthralgia; arthritis; bacillary angiomatosis; CSD; endocarditis; erythema; granulomatous hepatis; neuroretinitis; peliosis hepatis; pulmonary nodules; uveitis; vasoproliferative tumors |
| B. vinsonii berkhoffii | Endocardial fibrosis complex (NI); endomyocarditis - left ventricular; osteomyelitis (NI) | Anemia (NI); arrhythmias (NI); endocarditis (NI); epistaxis (NI); fever (NI); granulomatous lymphadenitis (NI); hemangiosarcoma (NI); myocarditis (NI); polyarthritis (NI); splenomegaly (NI); subclinical (EI, NI); thrombocytopenia (NI); uveitis (NI) | Endocarditis |
| B. clarridgeiae | NCR or subclinical | Endocarditis (NI); hepatic disease (NI) | CSD |
| B. quintana | NCR or subclinical | Endocarditis (NI); subclinical (NI) | Bacillary angiomatosis; endocarditis; fever; neuroretinitis; uveitis |
| B. koehlerae | Endomyocarditis - left ventricular; endocardial fibrosis complex | Endocarditis (NI); hyperinsulinemic hypoglycemia syndrome (NI); splenic disease (NI) | Endocarditis |
| B. rochalimae | NCR or subclinical (EI) | Endocarditis (NI); subclinical (EI) | Fever; splenomegaly |
| B. washoensis | NCR or subclinical | Endocarditis (NI) | Fever; myocarditis |
aDetails included in Table 6 are provided in [20–22, 29, 30, 39, 70, 91, 92, 96, 98, 99, 112, 127, 132, 136, 154, 160, 168–170, 289, 292–305]
bPathology reported in dogs to date is mainly due to natural infection only
Abbreviations: CSD cat scratch disease, EI experimental infection, NI natural infection, NCR not clearly related (the reports did not completely prove the direct relation between the clinical findings and the Bartonella infection or the animals had subclinical infection)