Table 2.
Patient characteristics
| Variable | Missing data, n (%) | Overall population (n = 7515) | Neutropenic patients (n = 1702)a | Non-neutropenic patients (n = 5810)a |
P
value |
|---|---|---|---|---|---|
| Age (years) | 15 (0.2%) | 60 (49–69) | 55 (41–64) | 61 (51–70) | < 0.001 |
| ICU admission year | 0 | 2007 (2004–2010) | 2008 (2005–2010) | 2007 (2004–2010) | < 0.001 |
| Underlying malignancy | |||||
| Solid tumors | 0 (0%) | 3366 (44.8%) | 232 (13.6%) | 3131 (53.9%) | < 0.001 |
| Hematological malignancy | 0 (0%) | 4149 (55.2%) | 1470 (86.4%) | 2679 (46.1%) | < 0.001 |
| Allogeneic HSCT | 0 (0%) | 439 (5.8%) | 186 (10.9%) | 253 (4.4%) | < 0.001 |
| SAPS II | 503 (6.7%) | 41 (28–57) | 51 (34–68) | 39 (26–54) | < 0.001 |
| Organ support at ICU admission | |||||
| Mechanical ventilation | 1 (0%) | 3804 (50.6%) | 964 (56.6%) | 2839 (48.9%) | < 0.001 |
| Vasopressors | 0 (0%) | 3084 (41%) | 954 (56.1%) | 2129 (36.6%) | < 0.001 |
| Renal replacement therapy | 58 (0.8%) | 1201 (16%) | 386 (22.7%) | 815 (14%) | < 0.001 |
| Mortality | 2 (0%) | 3538 (47.1%) | 1021 (60%) | 2517 (43.3%) | < 0.001 |
HSCT hematopoietic stem cell transplantation, SAPS Simplified Acute Physiology Score, ICU intensive care unit
aData on neutropenia unavailable in three patients (0.03%)