Table 3.

Estimated proportions of sPPH for the four trials, with two-sided 95% confidence intervals (CI), by the binomial and by the lognormal approaches: Misoprostol trial [17], Active Management trial [19], CHAMPION trial [18] and Althabe et al. trial [20]

Trial	Treatment	Proportion	95% CI		Width of the 95%CI	Width ratio lognormal vs binomial (%)
			Lower limit	Upper limit
Binomial
Misoprostol	Misoprostol	0.03962	0.03582	0.04380	0.00797	–
	Oxytocin	0.02839	0.02520	0.03199	0.00679	–
Active Management	Simplified Package	0.02057	0.01814	0.02331	0.00517	–
	Full Package	0.01885	0.01653	0.02148	0.00495	–
CHAMPION	Aggregated	0.01560	0.01400	0.01739	0.00339	–
Althabe et al	Hands Off	0.05102	0.02199	0.11392	0.09194	–
	CCT	0.02970	0.01015	0.08372	0.07356	–
Lognormal
Misoprostol	Misoprostol	0.02976	0.02740	0.03229	0.00490	61.4
	Oxytocin	0.01748	0.01582	0.01928	0.00346	51.0
Active Management	Simplified Package	0.01760	0.01603	0.01930	0.00327	63.2
	Full Package	0.01685	0.01532	0.01850	0.00317	64.0
CHAMPION	Aggregated	0.01737	0.01617	0.01865	0.00248	73.2
Althabe et al	Hands Off	0.03799	0.01655	0.07807	0.06151	66.9
	CCT	0.03250	0.01369	0.06885	0.05515	75.0