Table 7.

Severity of the “most bothersome symptoms” in the surrogate Rome IV FBD and IBS-C subjects

GI symptoms	0:Very mild	1:Mild	2:Moderate	3:Severe	4:Very Severe	p-value (Surrogate Rome IV FBD vs Surrogate Rome IV IBS-C)
Abdominal bloating
Surrogate Rome IV FBD subjects (n = 88)	0	4.5	28.4	52.3	14.8	n.s.
Surrogate Rome IV IBS-C subjects (n = 33)	6.1	3.0	12.1	54.5	24.2
Abdominal discomfort
Surrogate Rome IV FBD subjects (n = 48)	2.1	6.3	41.7	33.3	16.7	n.s.
Surrogate Rome IV IBS-C subjects (n = 27)	0	3.7	33.3	33.3	29.6
Abdominal pain
Surrogate Rome IV FBD subjects (n = N/A)	N/A	N/A	N/A	N/A	N/A	N/A
Surrogate Rome IV IBS-C subjects (n = 17)	5.9	5.9	23.5	52.9	11.8

Data are expressed as rate (%)

GI, gastrointestinal