Table 2.
The association between fifths of GIT scores and cause-specific mortality
| Mortality cause | Q1 | Q2 | Q3 | Q4 | Q5 | Total |
|---|---|---|---|---|---|---|
| a. Cause-specific death according to GIT quintiles | ||||||
| All-cause, N (%) | 8765 (1.97%) |
6306 (1.31%) |
6188 (1.41%) |
5221 (1.11%) |
4788 (1.09%) |
31,268 |
| Incidence (event/105 person-years) | 108.7 | 71.3 | 73.2 | 60.9 | 60.0 | 74.6 |
| Total cardiovascular, N (%) | 1075 (0.24%) |
641 (0.13%) |
624 (0.14%) |
394 (0.08%) |
334 (0.08%) |
3068 |
| Incidence (event/105 person-years) | 13.3 | 7.25 | 7.4 | 4.6 | 4.2 | 7.3 |
| Coronary heart disease, N (%) | 526 (0.12%) |
288 (0.06%) |
308 (0.07%) |
165 (0.03%) |
156 (0.04%) |
1443 |
| Incidence (event/105 person-years) | 6.5 | 3.3 | 3.6 | 1.9 | 1.9 | 3.4 |
| Stroke, N (%) | 172 (0.04%) |
115 (0.02%) |
110 (0.03%) |
72 (0.02%) |
45 (0.01%) |
514 |
| Incidence (event/105 person-years) | 2.1 | 1.3 | 1.3 | 0.8 | 0.6 | 1.2 |
| Diabetes, N (%) | 184 (0.04%) |
98 (0.02%) |
96 (0.02%) |
51 (0.01%) |
28 (0.01%) |
457 |
| Incidence (event/105 person-years) | 2.3 | 1.1 | 1.1 | 0.6 | 0.4 | 1.1 |
| Non-CVD, non-diabetes, N (%) | 7506 (1.68%) |
5567 (1.16%) |
5468 (1.24%) |
4776 (1.01%) |
4426 (1.01%) |
27,743 |
| Incidence (event/105 person-years) | 93.1 | 63.0 | 64.7 | 55.7 | 55.4 | 66.2 |
| b. Cox proportional hazard models | ||||||
| All cause (unadjusted) |
1.84 (1.78, 1.91) |
1.25 (1.20, 1.29) |
1.21 (1.16, 1.25) |
1.04 (1.00, 1.08) |
1 | 4.10*10−231 |
| All cause (adjusted) |
1.23 (1.17, 1.28) |
1.08 (1.04, 1.13) |
1.04 (1.00, 1.08) |
1.01 (0.98, 1.06) |
1 | 1.3*10−33 |
| Total CVD (unadjusted) | 3.32 (2.93, 3.75) |
1.92 (1.68, 2.19) |
1.71 (1.49, 1.95) |
1.15 (0.99, 1.33) |
1 | 2.13*10−126 |
| Total CVD (adjusted) |
1.76 (1.52, 2.04) |
1.44 (1.24, 1.66) |
1.27 (1.11, 1.46) |
1.05 (0.91, 1.22) |
1 | 1.3*10−14 |
| CHD (unadjusted) |
3.49 (2.92, 4.18) |
1.87 (1.54, 2.27) |
1.8 (1.48, 2.18) |
1.03 (0.83, 1.29) |
1 | 1.21*10−66 |
| CHD (adjusted) |
1.70 (1.37, 2.11) |
1.36 (1.09, 1.68) |
1.31 (1.07, 1.60) |
0.95 (0.76, 1.18) |
1 | 1.6*10−9 |
| Stroke (unadjusted) |
3.96 (2.85, 5.50) |
2.60 (1.84, 3.66) |
2.22 (1.57, 3.15) |
1.56 (1.08, 2.27) |
1 | 5.06*10−24 |
| Stroke (adjusted) |
2.03 (1.39, 2.98) |
1.83 (1.26, 2.66) |
1.61 (1.12, 2.30) |
1.40 (0.96, 2.03) |
1 | 3.3*10−6 |
| Diabetes (unadjusted) |
6.96 (4.68, 10.36) |
3.76 (2.47, 5.72) |
3.08 (2.02, 4.69) |
1.81 (1.14, 2.87) |
1 | 5.13*10−38 |
| Diabetes (adjusted) |
3.14 (2.00, 4.94) |
2.36 (1.5, 3.7) |
2.04 (1.32, 3.15) |
1.55 (0.97, 2.46) |
1 | 3.2*10−9 |
| Non CVD/diabetes (unadjusted) |
1.70 (1.64, 1.77) |
1.18 (1.13, 1.23) |
1.16 (1.11, 1.20) |
1.02 (0.98, 1.06) |
1 | 7.78*10−247 |
| Non CVD/diabetes (adjusted) |
1.17 (1.12, 1.22) |
1.04 (1.00, 1.09) |
1.01 (0.97, 1.05) |
1.01 (0.97, 1.05) |
1 | 1.3*10−19 |
The association between fifths of GIT scores (in comparison to highest quintile) and cause of death was determined using unadjusted and after adjustment for age, sex, birth year, body mass index (BMI), residential socioeconomic status, education and country of origin
HR Hazard ratio, CI confidence interval, CHD coronary heart disease, CVD cardiovascular