Table 4.
Variable | No. of patients (EDs) | Mean (SE) | Incremental cost, raw (95%CI)† | Incremental cost, adjusted (95%CI)‡ | ||
---|---|---|---|---|---|---|
Rx | Control | Rx | Control | |||
NET | ||||||
Rx Cost | ||||||
Base-case | 893 (14) | 1050 (17) | $139.0 (1.6) | $0.8 (0.0) | $138.20 (135,141) | – |
No URG | 893 (14) | 1050 (17) | $139.0 (1.6) | $0.8 (0.0) | $138.20 (135,141) | – |
HSU Cost | ||||||
Base-case | 893 (14) | 1050 (17) | $825.9 (44) | $777.4 (33) | $48.52 (− 57, 154) | $23.86 (− 106,153) |
No URG | 893 (14) | 1050 (17) | $354.0 (42) | $315.7 (31) | $38.35 (− 62, 139) | -$1.08 (− 125,122) |
Total Cost | ||||||
Base-case | 893 (14) | 1050 (17) | $964.9 (44) | $778.2 (33) | $186.72 (81, 292) | $169.89 (43, 297) |
No URG | 893 (14) | 1050 (17) | $493.0 (42) | $316.5 (31) | $176.55 (76, 277) | $159.96 (39, 281) |
NET-Plus, including post-NET HSU | ||||||
Rx Cost | ||||||
Base-case | 126 (10) | 218 (14) | $143.8 (4.6) | $0.8 (0.0) | $142.96 (136,150) | – |
No URG | 126 (10) | 218 (14) | $143.8 (4.6) | $0.8 (0.0) | $142.96 (136,150) | – |
HSU Cost | ||||||
Base-case | 126 (10) | 218 (14) | $980.8 (235) | $738.5 (72) | $242.38 (− 156,640) | $341.78 (− 58, 742) |
No URG | 126 (10) | 218 (14) | $526.6 (233) | $276.5 (66) | $250.06 (− 137,638) | $338.54 (− 56, 733) |
Total Cost | ||||||
Base-case | 126 (10) | 218 (14) | $1124.6 (235) | $739.3 (72) | $385.34 (− 12, 783) | $505.06 (96, 915) |
No URG | 126 (10) | 218 (14) | $670.3 (233) | $277.3 (66) | $393.02 (− 6, 780) | $543.49 (116, 971) |
†Incremental cost, raw = unconditional difference in cost per patient due to exposure to the intervention from two sample t test with equal variances
‡Incremental cost, adjusted = difference in cost due to exposure to the intervention; adjusted for the following minimisation factors and pre-specified confounders: age, sex, out_of_hours, rurality, mTBI protocol, ED participation in NET-Plus, and annual_presentation_rate. Estimates derived from margins, dydx(i.study_group) after xtgee, family(gamma) link(log) corr(exchangeable) vce(robust) to account for within-cluster correlation structure and yielding cluster-robust standard errors even if the correlation structure is misspecified