Fig. 6.
(A) Bar charts for the significantly affected intermediates of the interrelated pathways of glycolysis, pentose phosphate pathway (PPP), tricarboxylic acid cycle (TCA), and electron transport chain of P. aeruginosa FADDI-PA006 after polymyxin B (PMB, purple), tamoxifen (TAM, green), and the combination (COM, red) treatment at 1 h (≥ 1.0-log2-fold, p ≤ .05; FDR ≤ 0.05). (B) Schematic diagram for the impacted pathways (glycolysis, pentose phosphate pathway (PPP), tricarboxylic acid cycle (TCA), and electron transport) following treatment with polymyxin B, tamoxifen, and combination treatment at 1 h. Blue boxes indicated significantly impacted metabolites.