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. 2018 Oct 30;7(12):1370–1379. doi: 10.1530/EC-18-0386

Table 1.

Clinicopathological features of cases analyzed by NGS.

Group Num of cases Age (mean) (years) Sex Histology Fu (range) FU (event)
DM-PTC 29 53.0 11 M18 F 17 C-PTC8 TCV-PTC3 FV-PTC1 ST-PTC 101.7 ms (24–234) 15 DOD11 AWD2 NED1 NA
ATC 18 70.6 7 M11 F 18 ATC 27.9 ms (1–195) 11 DOD1 AWD2 DOC4 NA
HA-TC 47 59.7 18 M29 F 17 C-PTC8 TCV-PTC3 FV-PTC1 ST-PTC18 ATC 69.3 ms (1–234) 26 DOD12 AWD2 DOC2 NED5 NA
N0 32 54.9 6 M26 F 25 C-PTC2 TCV-PTC4 FV-PTC1 ST-PTC 136.3 ms (77–216) 30 NED2 NA
N1 34 49.1 13 M21 F 24 C-PTC6 TCV-PTC4 FV-PTC 157.2 ms (85–373) 5 AWD25 NED4 DOC
ctrl-PTCs 66 19 M47 F 49 C-PTC8 TCV-PTC8 FV-PTC1 ST-PTC 142.1 ms (77–373) 5 AWD55 NED4 DOC2 NA

ATC, anaplastic thyroid carcinoma; AWD, alive with disease; C-PTC, classic papillary thyroid carcinoma; ctrl-PTCs, control group (N0 + N1); DM-PTC, distantly metastatic PTC; DOC, dead of other cause; DOD, dead of disease; F, female; FU, follow-up; FV, follicular variant; HA-TC, highly aggressive thyroid carcinoma (DM-PTC + ATC); M, male; ms, months; N0, no lymph nodal involvement at presentation; N1, lymph nodal involvement at presentation; NA, not available; NED, not evidence of disease; ST, solid trabecular; TCV, tall-cell variant.