Table 2.
Contingency tables of relevant gene mutations.
DM-PTC (29) | ATC (18) | DM-PTC + ATC (47) | N0 + N1 (66) | |||
---|---|---|---|---|---|---|
% | % | % | % | |||
BRAF | 0.017 | 0.047 | ||||
wt | 62.01 (18) | 94.4 (17) | 74.5 (35) | 54.5 (36) | ||
mut | 37.9 (11) | 5.6 (1) | 25.5 (12) | 45.5 (30) | ||
GNAS | 0.283 | 0.158 | ||||
wt | 96.5 (28) | 83.3 (15) | 91.5 (43) | 98.5 (65) | ||
mut | 3.5 (1) | 16.6 (3) | 8.5 (4) | 1.5 (1) | ||
MED12 | 0.517 | 0.069 | ||||
wt | 93.1 (27) | 100 (18) | 95.7 (45) | 83.3 (55) | ||
mut | 6.9 (2) | 0 (0) | 4.3 (2) | 16.7 (11) | ||
MET | 0.517 | 0.118 | ||||
wt | 93.1 (27) | 100 (18) | 95.7 (45) | 86.4 (57) | ||
mut | 6.9 (2) | 0 (0) | 4.3 (2) | 13.6 (9) | ||
TERT | 0.549 | <0.0001 | ||||
wt | 51.7 (15) | 38.9 (7) | 46.8 (22) | 92.4 (61) | ||
mut | 48.3 (14) | 61.1 (11) | 53.1 (25) | 7.6 (5) | ||
TP53 | <0.0001 | 0.001 | ||||
wt | 100 (29) | 38.9 (7) | 76.6 (36) | 97 (64) | ||
mut | 0 (0) | 61.1 (11) | 23.4 (11) | 3 (2) |
Significance of differences on mutation frequency for the indicated genes was evaluated by Fisher exact test.