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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Acta Neuropathol. 2018 Jul 2;136(6):857–872. doi: 10.1007/s00401-018-1881-4

Table 3.

Genome-Wide Sex-Specific Effects

SNP Chr Gene+ Function CSF Aβ42
Male β
(SE)		 Male P Female β
(SE)		 Female P Interaction β
(SE)		 Interaction P
rs13115400 4 LINC00290 Intergenic 0.01
(0.01)		 0.20 0.03
(0.01) 		3.97×10−8 0.03
(0.01)		 0.002*
rs316341 6 SERPINB1 Intronic −0.02
(0.01)		 0.009 −0.03
(0.01) 		4.25×10−8 −0.02
(0.01)		 0.04*
SNP Chr Gene+ Function CSF Total Tau
Male β
(SE) 		Male P Female β
(SE) 		Female P Interaction β
(SE) 		Interaction P
rs1393060 3 GMNC Intergenic 0.02
(0.01)		 0.03 0.05
(0.01) 		4.57×10−10 0.03
(0.01)		 0.004*

Boldface font signifies genome-wide significant association

*

indicates interaction p<0.05.

+

Gene listed is the closest gene and may not be the functional gene.