Skip to main content
. Author manuscript; available in PMC: 2019 Apr 23.
Published in final edited form as: Angew Chem Int Ed Engl. 2018 Feb 23;57(18):4840–4848. doi: 10.1002/anie.201710407

Scheme 2.

Scheme 2.

Example of a macrocycle with 14 amino acids (Bristol-Myers Squibb Company WO2014151634 A1 compound 16). The IC50 value was determined by HTRF assay. The numbering of amino acids starts from the position adjacent to the sulfur and continues clock-wise.