Skip to main content
. Author manuscript; available in PMC: 2018 Dec 5.
Published in final edited form as: Cell Rep. 2018 Oct 30;25(5):1332–1345.e5. doi: 10.1016/j.celrep.2018.10.007

Figure 4. Integrated Analysis Reveals Genomic and Expression Alterations in Signaling Pathways in HNSCC Differing in HPV Status.

Figure 4.

See Figure S6 for workflow of analysis and Table S4 for detailed pathway analysis results.

(A and B) The key affected pathways, components, and cellular functions in (A) HPV(−) and (B) HPV(+) cell lines are presented.

The altered genes were analyzed for corresponding pathways by Ingenuity Pathway Analysis (IPA), and the workflow is summarized in Figure S6. Additional information is summarized in Table S4. Color key, fold expression compared with diploid: red, increased; green, decreased. Function, activation (arrows), inhibition (block). Large circles indicate biological complex, and ellipses indicate transmembrane receptors.