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Synergistic assay of BETi and SAHA.
Cell viability was measured after 48 and 72 hours of drug treatment using a luminescent ATP detection assay. (A) SAHA and OTX015, 48 hours; (B) SAHA and OTX015, 72 hours; (C) SAHA and JQ1, 48 hours; (D) SAHA and JQ1, 72 hours. CI value <1 indicates the drug combination is synergistic; CI value >1 indicates the combination is antagonistic.
