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Quantification of cell cycle analysis.
PI staining of total DNA content after 24 hours of JQ1 (1 μM), SAHA (1 μM), or combination (1 μM each) treatment. Combination of JQ1 with SAHA induces increased G0/G1 phase and reduced S phase in all CTCL cell lines. Data are presented as mean ± SD, n = 3, *P < .05, **P < .01 compared to either JQ1 or SAHA group.
