Skip to main content
. 2018 Nov 28;9:1368. doi: 10.3389/fphar.2018.01368

FIGURE 2.

FIGURE 2

Effects of IFN-β and STAT proteins on LPS-induced cytokine secretion: (A–E) CF were transfected with scramble or 200 ng of si-STAT1, si-STAT2, and si-STAT3 for 8 h, serum-deprived of for 24 h, pre-treated with IFN-β for 1 h, and stimulated with LPS for 24 h. (A) IL-6, (B) TNF-β, (C) IL-10, (D) MCP-1 and (E) IP-10 secretion to the culture medium was determined by LUMINEX assay. Error bars indicate the SD for three independent experiments. ∗∗∗p < 0.001, ∗∗p < 0.01, vs. scramble. +++p < 0.001 vs. scramble + LPS. ###p < 0.001, ##p < 0.01 vs. scramble + IFN-β + LPS. &&&p < 0.001, &&p < 0.01 vs. scramble + IFN-β.