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. 2018 Dec;10(12):a033092. doi: 10.1101/cshperspect.a033092

Figure 2.

Figure 2.

Structural models of eukaryotic initiation factor (eIF)3. A composite model of the structure of eIF3 showing the mammalian octamer (right) from PDB 5A5T (des Georges et al. 2015) and the associated eIF3d subunit (PDB 5K4D) (Lee et al. 2016) that is linked via eIF3a to the yeast-like core eIF3bgi complex (PDB 5A5U) (des Georges et al. 2015). The eIF3g is composed of an RNA-recognition motif (RRM) (PDB 2CQ0) and a β-propeller domain similar to eIF3b. eIF3j can interact with the eIF3b RRM. NTD, Amino-terminal domain.