FIG. 1.

Prostaglandin production by J774A.1 macrophages. Prostaglandin production from J774A.1 cells was measured by UPLC-ESI-MS/MS, and total area ratios were estimated for each sample. Data are expressed as fold change from vehicle (0.05% EtOH). Statistically significant differences were determined with one-way ANOVA with Duncan’s Studentized range test for multiple comparisons. Data represent the mean ± SEM of three experiments. Treatment groups with the same letter are not significantly different (P < .05). Abbreviations: UPLC, ultra-performance liquid chromatography; MS/MS, tandem mass spectrometry.