FIG. 2.
Inhibition of prostaglandin production in cell lysates. Production of (A) PGE2 and (B) PGF2α from exogenous AA was measured in J774A.1 cell lysates by UPLC-ESI-MS/MS and area ratios (analyte/internal standard) were estimated for each sample. Data are expressed as fold change from vehicle. Statistically significant differences were determined with one-way ANOVA with Duncan’s Studentized range test for multiple comparisons. Data represent the mean ± SEM of three experiments. Treatment groups with the same letter are not significantly different (P < .05).