Table 1.
Mean ± standard deviation of all hemodynamic or PET-derived parameters involved in calculation of myocardial external efficiency (MEE) for healthy controls, aortic valve stenosis (AVS), and mitral regurgitation (MVR) patients
| Controls (n = 10) | AVS (n = 33) | MVR (n = 20) | |
|---|---|---|---|
| SBP (mmHg) | 124 ± 11 | 139 ± 18* | 134 ± 15 |
| DBP (mmHg) | 79 ± 6 | 79 ± 11 | 71 ± 13† |
| HR (min−1) | 62 ± 8 | 65 ± 11 | 60 ± 12 |
| MAP (mmHg) | 97 ± 9 | 99 ± 12 | 92 ± 12† |
| MVO2 (mLO2·g−1·min−1) | 0.10 ± 0.02 | 0.12 ± 0.04 | 0.11 ± 0.03 |
| FCI (L·min−1·m−2) | 2.4 ± 0.4 | 2.6 ± 0.6 | 2.6 ± 0.4 |
| LVMI (g·m−2) | 63.8 ± 8.4 | 89.3 ± 25.0** | 90.5 ± 17.2*** |
| EW (J) | 60.9 ± 15.0 | 66.2 ± 21.0 | 64.3 ± 14.6 |
| TE (J) | 260 ± 57 | 399 ± 137** | 385 ± 152* |
| MEE (%) | 23.6 ± 4.2 | 17.2 ± 4.3*** | 18.0 ± 5.2** |
SBP, systolic blood pressure; DBP, diastolic blood pressure; HR, heart rate; MAP, mean arterial pressure; MVO2, rate of oxygen consumption; FCI, forward cardiac index; LVMI, left ventricular mass corrected for body-surface area; EW, external work; TE, total energy usage
*, ** and ***P < 0.05, < 0.01 and < 0.001 vs healthy controls
†P < 0.05 vs AVS