Table 1.
Laboratory values
| Patient | A | B |
| Sex | M | M |
| Age (years) | 55 | 88 |
| Liver function tests | ||
| ALT (IU/L, normal values < 35) | 3133 | 59 |
| AST (IU/L, normal values < 45) | 1788 | 61 |
| Bilirubin (μM, normal values < 34) | 241 | 11 |
| INR | 1.12 | 1.21 |
| CSF analysis | ||
| Protein (g/L) | 0.42 | 0.69 |
| Erythrocytes/mL | 0 | 6 |
| White blood cells/mL | 4 | 3 |
| Serology | ||
| Anti-HBc IgM | POS | NEG |
| Anti-HBc IgG | NEG | POS |
| HBe Ag | POS | POS |
| Anti-HBe Ab | NEG | NEG |
| Anti-HDV Ab | NEG | NEG |
| HBV markers | ||
| Genotype | A2 | A2 |
| Plasma HBV-VL (log10) IU/mL | 18,983 (4.28) | 250,940,372 (8.40) |
| Serum HBsAg (log10) IU/mL | 15,000 (4.18) | 39,000 (4.59) |
| CSF HBV-VL (log10) IU/mL | 280 (2.44) | 1000 (3) |
| CSF HBsAg (log10 ) IU/mL | 2.22 (0.34) | 7.3 (0.86) |
| Plasma HBsAg/HBV-VL ratio | 0.79 | 0.00015542 |
| CSF HBsAg/HBV-VL ratio | 0.0079 | 0.0073 |
| Blood/CSF VL ratio | 68 | 250,940 |
| Blood/CSF HBsAg ratio | 6757 | 5342 |