Table 2.
Capsule characteristics
| Characteristic | B1 | B4 | P |
|---|---|---|---|
| Entire capsule | |||
| Thickness | 543 ± 152 µm | 1802 ± 1035 µm | 0.004 |
| Inner layer | |||
| Present | Y (8/10) | Y (2/10) | 0.031 |
| Vimentin | Y (8/8) | Y (1/2) | |
| CD68 | Y (8/8) | Y (2/2) | |
| Cytokeratin | N (8/8) | N (2/2) | |
| Vim +/CD68 +/Cytokeratin- | 8/10 | 1/10 | 0.016 |
| Intermediate and outer layer | |||
| Vimentin | +(3/10) | +(0/10) | |
| ++(3/10) | ++(4/10) | ||
| +++(4/10) | +++(6/10) | ||
| CD68 | +(8/10) | +(5/10) | |
| ++(1/10) | ++(3/10) | ||
| +++(1/10) | +++(2/10) | ||
| Cytokeratin | −(10/10) | −(10/10) | |
| Cell density | +(7/10) | +(3/10) | |
| ++(2/10) | ++(6/10) | ||
| +++(1/10) | +++(1/10) | ||
Summary of morphological and histological characteristics of the capsules. Thickness in µm ± standard deviation, measured at fourfold magnification using NIS-Elements AR 2.10 software (Nikon). In each photo, at least 5 measurements were made. Cell density, inner layer presence and positive staining scored visually by two independent authors noting if an inner layer was present (Y), if that layer showed positivity (Y) or not (N) and for the outer layer, if it had low (+), medium (++) or high cell density (+++), positivity for the staining and whether it showed no (−), low (+), intermediate (++) or a lot (+++) of positive cells