Table S2.

Adverse pregnancy outcomes in singleton births to women with autism, without medication during pregnancy, Sweden, 2006–2014.

Outcome variables		Cases in women with autism (n=1,189)	Cases in population controls (n=8,08,570)	Crude OR; 95% CI	Adjusted OR;a 95% CI
Preterm birth	Preterm birth, all	76 (6.4)	36,915 (4.6)	1.43; 1.13–1.80	1.32; 1.04–1.67
	Preterm birth <28 weeks	5 (0.4)	1,965 (0.2)	1.73; 0.72–4.18	1.66; 0.69–4.00
	Preterm birth 28 to <32 weeks	6 (0.5)	3,4060 (0.4)	1.20; 0.54–2.68	1.12; 0.50–2.50
	Preterm birth 32 to <37 weeks	65 (5.5)	31,544 (3.9)	1.42; 1.11–1.83	1.31; 1.02–1.69
	Spontaneous preterm birthb	46 (3.9)	22,940 (2.8)	1.38; 1.02–1.85	1.24; 0.92–1.67
	Medically indicated preterm birthb	30 (2.5)	13,643 (1.7)	1.50; 1.05–2.17	1.46; 1.01–2.10
Mode of delivery	Cesarean delivery	199 (16.7)	1,30,749 (16.2)	1.04; 0.90–1.21	1.24; 1.06–1.44
	Elective cesarean delivery	111 (9.3)	65,467 (8.1)	1.17; 0.96–1.42	1.45; 1.19–1.13
	Not elective cesarean delivery	88 (7.4)	65,282 (8.1)	0.91; 0.73–1.13	1.01; 0.81–1.26
	Induction of delivery, all	203 (17.1)	1,05,746 (13.1)	1.37; 1.18–1.59	1.40; 1.20–1.63
Apgar score	Apgar score <7 at 5 minutes	11 (0.9)	9,912 (1.2)	0.75; 0.42–1.36	0.73; 0.40–1.33
Intrauterine growth	SGA	138 (11.7)	76,411 (9.5)	1.26; 1.06–1.51	1.23; 1.02–1.47
	LGA	106 (9.0)	79,324 (9.8)	0.90; 0.74–1.10	0.89; 0.73–1.10
Stillbirth	Stillbirth	5 (0.4)	2,383 (0.3)	1.43; 0.59–3.44	1.42; 0.59–3.43
Maternal complications	Preeclampsia	44 (3.7)	21,414 (2.6)	1.41; 1.04–1.91	1.26; 0.93–1.71
	Gestational diabetes	14 (1.2)	8,867 (1.1)	1.08; 0.63–1.82	1.36; 0.80–2.32

Notes: Data are n (%) unless otherwise specified. Statistically significant risk estimates were italicized and bold.

^aORs were adjusted for maternal age, country of maternal birth, smoking, body mass index, parity, and year of birth.

^bWe did not have data on spontaneous vs induced preterm birth in all preterm births, hence numbers do not add up.

Abbreviations: LGA, large for gestational age; SGA, small for gestational age.