Table 3.

Clinical, Laboratory, and Echocardiographic Characteristics of Patients With End-Stage Renal Disease on Dialysis Hospitalized With Infective Endocarditis, Stratified by Early Surgery

	Overall (n = 229)	Early Surgery (n = 67)	No Early Surgery (n = 162)	P Value
	No. (%) or Median (25th, 75th Percentile)
Altered mental status (n = 227)	67 (29.5)	12 (17.9)	55 (34.4)	.01
Any vascular phenomena	92 (40.2)	28 (41.8)	64 (39.5)	.75
Cerebrovascular accident (n = 228)	55 (24.12)	12 (17.9)	43 (26.7)	.16
Pulmonary embolus (n = 228)	9 (4.0)	3 (4.5)	6 (3.7)	.79
Intracranial hemorrhage	15 (6.6)	1 (1.5)	14 (8.6)	.07
Severe neurological damage (n = 225)	18 (8)	1 (1.5)	17 (10.6)	.03
Concurrent infection	63 (27.5)	11 (16.4)	52 (32.1)	.02
New-onset congestive heart failure	31 (13.6)	25 (37.3)	6 (3.7)	<.0001
Involved valve
Aortic	98 (42.8)	38 (56.7)	60 (37.0)	.006
Mitral	155 (67.7)	43 (64.2)	112 (69.1)	.47
New valvular regurgitation (n = 227)	136 (59.9)	57 (87.7)	79 (48.8)	<.0001
Intracardiac abscess or fistula (n = 219)	31 (14.2)	20 (32.3)	11 (7.0)	<.0001
Valvular vegetation	210 (91.7)	63 (94.0)	147 (90.7)	.60
Large vegetation (n = 145)	84 (57.9)	33 (76.7)	51 (50.0)	.003
Valve rupture (n = 220)	66 (30)	40 (61.5)	26 (16.8)	<.0001
Fever on admission (n = 209)	51 (24.4)	10 (19.6)	41 (26.8)	.18
Laboratory values
Hematocrit	31.1 (27.5, 35.1)	30.2 (27.3, 33.1)	31.4 (27.5, 35.9)	.19
White blood cell count × 1000/mm3	11.3 (8.6, 16.0)	12.1 (8.9, 16.1)	11.2 (8.4, 16.0)	.55
Platelet count × 1000/mm3	212 (155, 273)	232 (190, 322)	198.5 (137, 263)	.002
Glucose, mg/dL	112 (90, 147)	109 (91, 137)	113.5 (87, 149)	.88
Albumin, g/dL	2.6 (2.2, 3.0)	2.6 (2.2, 2.9)	2.7 (2.2, 3.1)	.42
Blood urea nitrogen, mg/dL	42 (30, 64)	37 (28, 52)	46 (31, 67)	.03