Table 4.
Microbiological Characteristics of Patients With End-Stage Renal Disease on Dialysis Hospitalized With Infective Endocarditis, Stratified by Early Surgery
| Overall (n = 229) |
Early Surgery (n = 67) |
No Early Surgery (n = 162) |
P Value | |
|---|---|---|---|---|
| No. (%) | ||||
| Gram-positive cocci | 201 (87.8) | 57 (85.1) | 144 (88.9) | .42 |
| Staphylococcus aureus | 104 (45.4) | 23 (34.3) | 81 (50.0) | .03 |
| MSSA | 53 (23.1) | 11 (16.4) | 42 (25.9) | .12 |
| MRSA | 51 (22.3) | 12 (17.9) | 39 (24.1) | .31 |
| VISA | 3 (1.3) | 3 (4.5) | 0 (0) | .02 |
| Coagulase-negative staphylococci | 53 (23.1) | 27 (40.3) | 26 (16.1) | <.0001 |
| Methicillin resistant | 26 (11.4) | 13 (19.4) | 13 (8.0) | .01 |
| Streptococci | 7 (3.1) | 2 (3.0) | 5 (3.1) | 1.0 |
| Enterococci | 37 (16.2) | 5 (7.5) | 32 (19.8) | .03 |
| VRE | 7 (3.1) | 0 (0) | 7 (4.3) | .11 |
| Gram-negative rods | 2 (0.9) | 1 (1.5) | 1 (0.6) | .50 |
| ESBL-producing GNR | 1 (0) | 0 (0) | 1 (0.6) | 1.0 |
| Corynebacterium jeikeium | 1 (0.4) | 1 (1.5) | 0 (0) | .59 |
| Fungi | 2 (0.9) | 0 (0) | 2 (1.2) | 1.0 |
| No growth | 23 (10.4) | 8 (11.9) | 15 (9.3) | .54 |
| Difficult-to-treat organism | 13 (5.7) | 3 (4.5) | 10 (6.2) | .76 |
| Persistently positive blood cultures (n = 223) | 12 (5.4) | 2 (3.1) | 10 (6.3) | .52 |
| Persistent fever (n = 199) | 22 (11.1) | 6 (10.7) | 16 (11.2) | .92 |
Abbreviations: ESBL, extended-spectrum beta-lactamase; GNR, Gram-negative rods; MRSA, methicillin-resistant Staphylococcus aureus; MSSA, methicillin-sensitive S. aureus; VISA, vancomycin-intermediate S. aureus; VRE, vancomycin-resistant enterococci.