Table 6.
Characteristics of Patients With End-Stage Renal Disease on Dialysis Hospitalized With Infective Endocarditis, Stratified by Transfer From an Outside Hospital
| Overall (n = 228) |
OSH Transfer (n = 77) |
No OSH Transfer (n = 151) |
P Value | |
|---|---|---|---|---|
| No. (%) or Median (25th, 75th Percentile) | ||||
| Age, y | 57 (48, 65.5) | 55 (47, 64) | 57 (50, 66) | .30 |
| Female sex | 112 (48.9) | 37 (48.1) | 75 (48.7) | .60 |
| Black race (n = 221) | 191 (86.0) | 53 (72.6) | 138 (92.6) | <.0001 |
| Diabetes mellitus | 110 (48.3) | 45 (58.4) | 65 (43.1) | .03 |
| HIV infection | 16 (7.0) | 0 (0) | 16 (10.6) | .002 |
| Chronic corticosteroid use | 15 (6.6) | 5 (6.5) | 10 (6.6) | 1.0 |
| IV drug use (n = 210) | 2 (0.9) | 0 (0) | 2 (1.4) | 1.0 |
| History of IE (n = 226) | 14 (6.2) | 6 (8) | 8 (5.3) | .42 |
| Existing valve disease (n = 223) | 102 (45.7) | 27 (36.5) | 75 (50.3) | .051 |
| Prosthetic valve | 26 (11.4) | 12 (15.6) | 14 (9.3) | .16 |
| Dialysis access | ||||
| IV catheter | 114 (52.1) | 35 (49.3) | 79 (53.4) | .57 |
| Other access | 105 (47.9) | 36 (50.7) | 69 (46.6) | |
| Time since dialysis initiation (n = 223), mo | 37 (13, 75) | 23.5 (9, 60.5) | 39 (14, 79) | .089 |
| Duration of dialysis access (n = 164), wk | 32 (11, 86.5) | 32 (15, 68) | 35 (10, 89) | .76 |
| Any Class I indication (n = 204) | 95 (46.6) | 40 (61.5) | 55 (39.6) | .003 |
| New CHF (n = 227) | 31 (13.7) | 17 (22.4) | 14 (9.3) | .007 |
| New conduction delay (n = 209) | 29 (13.9) | 7 (10.1) | 22 (15.7) | .27 |
| Abscess or fistula (n = 218) | 31 (14.2) | 17 (24.6) | 14 (9.4) | .003 |
| Difficult-to-treat organism | 13 (5.7) | 5 (6.5) | 8 (5.3) | .77 |
| Persistent infection (n = 196) | 29 (14.8) | 10 (16.7) | 19 (14.0) | .62 |
| Any Class IIa indication | 69 (30.3) | 33 (42.9) | 36 (23.8) | 0.003 |
| Recurrent emboli with persistent vegetation (n = 215) | 12 (5.6) | 4 (5.7) | 8 (5.5) | 1.0 |
| Valve regurgitation and mobile vegetation >10 mm (n = 227) | 56 (24.8) | 27 (35.5) | 29 (19.3) | .008 |
| Prosthetic valve IE with recurrent emboli (n = 223) | 2 (0.9) | 2 (2.7) | 0 (0) | .11 |
| Relapsing prosthetic valve IE (n = 225) | 7 (3.1) | 3 (4.0) | 4 (2.7) | .69 |
| Class IIb indication | ||||
| Mobile vegetation >10 mm (n = 144) | 83 (57.6) | 33 (76.7) | 50 (49.5) | .003 |
| Any contraindication | 28 (12.3) | 13 (16.9) | 15 (9.9) | .13 |
Abbreviations: CHF, congestive heart failure; IE, infective endocarditis; IV, intravenous; OSH, outside hospital.