Table 8.

Predictors of Surgical Intervention Among Patients With ESRD and Left-Sided IE in Bivariate Modeling

Variable	Odds Ratio	95% Confidence Interval	P Value
Age at diagnosis	0.97	0.94–0.99	.003
Outside hospital transfer	4.71	2.56–8.68	<.0001
Altered mental status	0.43	0.21–0.87	.02
Concurrent infection	0.37	0.18–0.78	.009
Aortic valve involvement	2.33	1.30–4.17	.004
New regurgitation	7.49	3.36–16.69	<.0001
Large vegetation	2.20	1.22–3.94	.008
Valve rupture	8.33	4.31–16.10	<.0001
Existing valve disease	0.37	0.20–0.68	.002
Multivalve disease	4.12	1.73–9.84	.001
Staphylococcus aureus	0.49	0.73–0.90	.02
Coagulase-negative staphylococci	3.65	1.91–6.96	<.0001
Methicillin-resistant	2.83	1.23–6.49	.01
Platelet count	1.004	1.001–1.006	.01
Any Class I indication	4.05	2.12–7.74	<.0001
New CHF	15.85	6.1–41.2	<.0001
Abscess or fistula	6.52	2.89–14.70	<.0001
Any Class IIa indication	3.41	1.86–6.24	<.0001
Large vegetation with recurrent emboli	3.47	1.84–6.55	.0001
Contraindication to surgery	0.16	0.04–0.72	.02

Abbreviations: CHF, congestive heart failure; ESRD, end-stage renal disease; IE, infective endocarditis.