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. 2016 May 21;31(5):491–509. doi: 10.1093/mutage/gew019

Table 3.

Induction of lung cancer in mice with low-LET ionising radiation

Malignancy Mouse strain Age Sex Dosage Fractionation Latency Spontaneous frequency Induced frequency Ref.
Lung Cancer C3H (C3H/HeSlc) 6 weeks Male 7.5 Gy thoracic 2 doses, 12-h interval 12 months 3.5–9.5% 40% (232,233)
Lung Cancer RFM (RFM/Un) 10–12 weeks Female 9 Gy thoracic single 9 months ~28% 87% (235,236)
Lung Cancer BALB/c (BALB/c/An) 12 weeks Female 2 Gy TBI single 12 months ~12% ~37% (237,238)