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. 2016 Jun 24;75(8):779–790. doi: 10.1093/jnen/nlw056

FIGURE 6.

FIGURE 6.

Quantification of BIN1 immunoreactivity yields similar results in PFC and CA1. (A) Subject group (non-AD/BB0-III; AD/BBIV-V) and anatomical region (CA1; PFC Layer III; PFC Layer V-VI) show significant overall effect in BIN1-immunoreactive (-ir) neuropil area (p < 0.0001 for both) by two-way ANOVA. Significant interaction between subject group and anatomical area also exists (p = 0.019). (B) BIN1-ir pyramidal neurons show a significant subject group overall effect (p < 0.0001).