Fig 1.

Mer^KD mice have delayed resolution of allergic airway inflammation in vivo.A, Schema of the experimental protocol. i.p., Intraperitoneal. B and C, BALF eosinophils in WT (Fig 1, B) and Mer^KD (Fig 1, C) mice at 1, 3, 7, and 10 days after OVA, with Δ change in eosinophil numbers between day 3 and day 7 shown (n = 7-10). D, Interstitial eosinophils at day 7 in WT and Mer^KD mice (n = 6-8). E and F, Representative lung sections stained with hematoxylin and eosin at day 7 after OVA from WT (Fig 1, E) and Mer^KD (Fig 1, F) mice (×100 original magnification). Scale bar = 20 μm. G, Quantification of hematoxylin and eosin–stained lung sections at 7 days after OVA treatment (n = 5). Data are expressed as means ± SEMs and analyzed by means of 1-way ANOVA with the Newman-Keuls multiple comparison test (Fig 1, B and C) or the Student t test (Fig 1, D and G), *P < .05, **P < .01, and ***P < .001. IT-OVA, Intratracheal ovalbumin; ns, not significant.