Table 1.
Demographic and clinical features of the study participants.
| HCs subjects (n = 22) | MHE patients (n = 22) | P value | |
|---|---|---|---|
| Age (years) | 51.8 ± 6.5 | 51.3 ± 8.9 | 0.848 |
| Sex (male/female) | 15/7 | 17/5 | 0.498 (χ2 test) |
| Education level (years) | 8.7 ± 2.2 | 8.8 ± 2.7 | 0.812 |
| Etiology of cirrhosis (HBV/alcoholism/HBV+alcoholism/other) | - | 13/4/2/3 | - |
| Child-Pugh stage (A/B/C) | - | 3/13/6 | - |
| Final PHES score | 0.7 ± 2.2 | −8.2 ± 3.0 | <0.001 |
| Number connection test A (s) | 37.0 ± 12.3 | 57.3 ± 17.3 | <0.001 |
| Number connection test B (s) | 63.8 ± 29.2 | 134.2 ± 62.3 | <0.001 |
| Serial dotting test (s) | 43.0 ± 7.6 | 65.3 ± 18.5 | <0.001 |
| Digit symbol test (raw score) | 45.2 ± 9.3 | 26.9 ± 8.5 | <0.001 |
| Line tracing test (raw score) | 115.8 ± 16.1 | 192.3 ± 47.3 | <0.001 |