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. 2018 Dec;43(12):758–763.

Table 2.

Selected Pharmaceutical Treatments for Insomnia21,27

Agent (Generic Name) Dosage Forms Indications/Comments
Non-benzodiazepines
Eszopiclone 1-mg, 2-mg, and 3-mg tablets Primarily used for sleep-onset and maintenance insomnia; intermediate-acting; no short-term usage restriction
Zolpidem 5-mg, 10-mg tablets Primarily used for sleep-onset insomnia; short-to intermediate-acting; primarily used for sleep-onset and maintenance insomnia; controlled-release
Zaleplon 5-mg, 10-mg capsules Primarily used for sleep-onset insomnia; maintenance insomnia as long as a 4-hour period is available for further sleep; short-acting
Benzodiazepines
Estazolam 1-mg, 2-mg tablets Short-to intermediate-acting
Temazepam 7.5-mg, 15-mg, and 30-mg capsules Short-to intermediate-acting
Triazolam 0.125-mg, 0.25-mg tablets Short-acting
Flurazepam 15-mg, 30-mg capsules Long-acting; risk of residual daytime drowsiness
Melatonin Receptor Agonists (Non-Scheduled)
Ramelteon 8-mg tablet Primarily used for sleep-onset insomnia; short-acting; no short-term usage restriction
Orexin Receptor Antagonist
Suvorexant 5-mg, 10-mg, 15-mg, and 20-mg tablets Indicated for the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance. Lowest effective dose should be used.