Table 1.
Non-significant long-term effects of pilocarpine-induced SE (Pilo-SE) on hippocampal pre-rRNA
| Experimental Group (n) |
Amplicon/Normalizing gene (mean fold control ± SEM) | |||
|---|---|---|---|---|
|
| ||||
| 5’ETS/18S | 5’ETS/Gapdh | ITS1/18S | ITS1/Gapdh | |
|
| ||||
| Control (9) | DGa: 1 ± 0.067 | DG: 1 ± 0.094 | DG: 1 ± 0.097 | DG: 1 ± 0.134 |
| CAb: 1 ± 0.095 | CA: 1 ± 0.065 | CA: 1 ± 0.083 | CA: 1 ± 0.13 | |
|
| ||||
| 1 week post Pilo-SE (6) | DG: 1.11 ± 0.13 c | DG: ND d | DG: 0.99 ± 0.13 c | DG: ND |
| CA: 0.99 ± 0.12 c | CA: ND | CA: 0.98 ± 0.12 c | CA: ND | |
|
| ||||
| 6 weeks post Pilo-SE (8) | DG: 1.29 ± 0.193c | DG: 1.05 ± 0.1 c | DG: 1.15 ± 0.13 c | DG: 1.01 ± 0.13 c |
| CA: 1.08 ± 0.11 c | CA:1.04 ± 0.06 c | CA: 0.94 ± 0.12 c | CA: 0.9 ± 0.067 c | |
a
dentate gyrus;
b
cornu Ammonis;
c
p>0.05, u-test as compared to the control group;
d
not determined.