Figure 7.
LCP-GMP inhibited melanoma tumor growth. Groups of C57BL/6 mice (n=10 per group) were inoculated with 5× 10 5 B16F10 cells s.c. on day 0. Melanoma-bearing mice received i.v. injections of LCP-GMP, Gem or control LCP on days 8, 10, 12 and 14, with a dose of 50.4 µmol/Kg GMP (or Gem). (A) Tumor volumes and (B) relative body weights were recorded during treatments. (C) Tumor weights on day 16 were shown. ***p<0.001, Untreated vs. LCP-GMP; *p<0.05, LCP-GMP vs. Gem.