Table 1. Demographic subjects of pregnant women undergoing non-invasive prenatal testing (NIPT) for aneuploidies between 1 March and 31 July in 2016.
| Subject a | Total | % of all | Negative | % in group | % of all | Positive b | % in group | % of all | P13 | % in group | % of all | P18 | % in group | % of all | P21 | % in group | % of all |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5518 | 5472 | 99.18 | 0.82 | 5 | 0.09 | 14 | 0.25 | 27 | 0.49 | ||||||||
| Age c | 31.83 | (15–47) | 31.83 | (15–47) | 31.70 | (20–43) | 31.2 | (25–40) | 29.57 | (23–42) | 32.59 | (20–43) | |||||
| <24 | 700 | 12.69 | 691 | 12.63 | 98.71 | 9 | 20.00 | 1.29 | 0 | 0.00 | 0.00 | 4 | 28.57 | 0.57 | 5 | 18.52 | 0.71 |
| 25–29 | 1285 | 23.29 | 1273 | 23.26 | 99.07 | 12 | 26.67 | 0.93 | 3 | 60.00 | 0.23 | 5 | 35.71 | 0.39 | 4 | 14.81 | 0.31 |
| 30–34 | 1371 | 24.85 | 1368 | 25.00 | 99.78 | 3 | 6.67 | 0.22 | 0 | 0.00 | 0.00 | 1 | 7.14 | 0.07 | 3 | 11.11 | 0.22 |
| 35–40 | 1741 | 31.55 | 1727 | 31.55 | 99.20 | 14 | 31.11 | 0.80 | 1 | 20.00 | 0.06 | 1 | 7.14 | 0.06 | 12 | 44.44 | 0.69 |
| >40 | 421 | 7.63 | 414 | 7.56 | 98.34 | 7 | 15.56 | 1.66 | 1 | 20.00 | 0.24 | 3 | 21.43 | 0.71 | 3 | 11.11 | 0.71 |
| Week c | 17.19 | (8–37) | 17.2 | (8–37) | 15.93 | (12–21) | 13.6 | (12–15) | 16.21 | (12–20) | 16.33 | (12–21) | |||||
| <13 | 651 | 11.80 | 643 | 11.75 | 98.77 | 8 | 17.78 | 1.23 | 2 | 40.00 | 0.31 | 1 | 7.14 | 0.15 | 5 | 18.52 | 0.77 |
| 14–27 | 4807 | 87.11 | 4770 | 87.16 | 99.23 | 37 | 82.22 | 0.77 | 3 | 60.00 | 0.06 | 13 | 92.86 | 0.27 | 22 | 81.48 | 0.46 |
| >28 | 60 | 1.09 | 60 | 1.10 | 100.00 | 0 | 0.00 | 0.00 | 0 | 0.00 | 0.00 | 0 | 0.00 | 0.00 | 0 | 0.00 | 0.00 |
| CostDay c | 10.39 | (5–62) | 10.38 | (5–62) | 10.80 | (6–18) | 10 | (8–14) | 12.07 | (7–18) | 10.11 | (6–17) | |||||
| <7 | 956 | 17.33 | 947 | 17.30 | 99.06 | 9 | 20.00 | 0.94 | 0 | 0.00 | 0.00 | 2 | 14.29 | 0.21 | 7 | 25.93 | 0.73 |
| 8–14 | 3963 | 71.82 | 3933 | 71.86 | 99.24 | 30 | 66.67 | 0.76 | 5 | 100.00 | 0.13 | 9 | 64.29 | 0.23 | 17 | 62.96 | 0.43 |
| 15–21 | 561 | 10.17 | 555 | 10.14 | 98.93 | 6 | 13.33 | 1.07 | 0 | 0.00 | 0.00 | 3 | 21.43 | 0.53 | 3 | 11.11 | 0.53 |
| >22 | 38 | 0.69 | 38 | 0.69 | 100.00 | 0 | 0.00 | 0.00 | 0 | 0.00 | 0.00 | 0 | 0.00 | 0.00 | 0 | 0.00 | 0.00 |
Demographic characteristics of pregnant women undergoing NIPT for aneuploidies in this study.
a Age means the age of the pregnant mother while doing the NIPT; Week means the gestational week while doing the NIPT; CostDay means the time cost in our NIPT service.
b Positive means the trisomy in either chromosome 13, 18 or 21. If none of these three chromosomes were found trisomy, the sample would be regarded as Negative in this study. P13 means trisomy in chromosome 13; P18 means trisomy in chromosome 18; P21 means trisomy in chromosome 21.
c Average values of relevant subjects with minimums and maximums in the brackets.