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. 2018 Dec 5;13(12):e0207298. doi: 10.1371/journal.pone.0207298

Table 3. Frequency of short-term newborn outcomes in each study group.

Adverse outcome Number of newborns completing evaluation MATERNAL PTB GROUPS P value
No-IAI Yes-IAI PE
IVH (grades 1–4) 372
    Present 15 (11) 25 (22) 13 (10) 0.024
    Absent 116 (89) 91 (78) 112 (90)
NEC (grades 2–4) 372
    Present 7 (5) 14 (12) 4 (3) 0.017
    Absent 124 (95) 102 (88) 121 (97)
PVL 371
    Present 4 (3) 4 (3) 3 (2) 0.888
    Absent 126 (97) 112 (97) 122 (98)
BPD 349
    Present 14 (13) 19 (18) 20 (19) 0.320
    Absent 110 (87) 89 (82) 97 (81)
ROP (grades 1–4) 371
    Present 13 (10) 38 (33) 28 (22) <0.001
    Absent 117 (90) 78 (67) 97 (78)
Fetal and neonatal death 378
    Present 7 (5) 10 (9) 14 (11) 0.283
    Absent 124 (95) 106 (91) 117 (89)
EONS 371
    Present 19 (15) 51 (44) 22 (18) <0.001
    Absent 112 (85) 65 (56) 102 (82)
Confirmed EONS 372
    Present 5 (4) 5 (4) 2 (2) 0.440
    Absent 126 (96) 111 (96) 123 (98)
Confirmed LOS 361
    Present 10 (8) 30 (28) 29 (23) <0.001
    Absent 118 (92) 78 (72) 96 (77)

† Data presented as n (%) and analyzed by Chi square tests.

Abbreviations: IVH, intra-ventricular hemorrhage; NEC, necrotizing enterocolitis; PVL, periventricular leukomalacia; BPD, bronchopulmonary dysplasia; ROP, retinopathy of prematurity; PTB, preterm birth; IAI, intra-amniotic inflammation/infection; PE, preeclampsia, EONS, early-onset neonatal sepsis; LOS, late-onset sepsis