Skip to main content
. 2018 Dec 5;12(12):e0006998. doi: 10.1371/journal.pntd.0006998

Fig 3. Increased frequency of TTE cells in patients with chronic Chagas disease.

Fig 3

PBMCs were stained with FV510, CD45RA, CD8, CD4, CD127, and CD132 monoclonal antibodies and analyzed using flow cytometry. Each symbol represents the proportion of CD127—CD132+ cells in total CD4+CD45RA+ (A) or CD8+CD45RA+ (B) T cell populations from IFN-γ producers (P) and IFN-γ nonproducers (NP), as classified according to ELISPOT responses as defined in Materials and Methods. Median values are indicated as horizontal lines. Black symbols indicate subjects treated with benznidazole. Comparisons between P and NP for each clinical group and uninfected subjects were performed using ANOVA followed by Dunn’s multiple comparisons test. (A) ## p ≤ 0.01 compared to NP G1 and NP G2-G3; ### p ≤ 0.001 compared with P G1 and NP G0; #### p ≤ 0.0001 compared with P G0 and P G2-G3; (B) ## p ≤ 0.001 compared with P G0 and NP G0.