Table 3. Factors independently associated with AKI after adjustment for confounders (stepwise logistic regression).

(Co) variable	Multivariate
	Initial			Restricted
	p-value	OR	95%- CI	p-value	OR	95%- CI
Aquaporin 5 –1364A/C genotype
- AC/CC	-	1		-	1
- AA	0.025	3.203	1.516–8.874	0.017	3.350	1.244–9.021
Age [per year]	0.045	1.033	1.000–1.067	0.048	1.020	1.000–1.046
Dialysis [no]	-	1
Dialysis [yes]	0.302	0.584	0.210–1.622
ECMO [no]	-	1
ECMO [yes]	0.122	0.404	0.132–1.235
Cumulative fluid balance on day 30
-2.5L - +2.5L	-	1	1
< -2.5L	0.432	0.639	0.209–1.953
> +2.5L	0.398	1.728	0.486–6.139

OR: Odds ratio point estimates, 95% CI, and p-values (two-sided) are reported. Homer-Lemeshow statistics were as follows: κ² = 13.2; p = 0.104